RESEARCH UPDATE: Helping HDL Cholesterol Work Even Better
A novel study by researchers at Penn State University provides insights into how eating almonds may benefit heart health, by boosting the most beneficial type of HDL cholesterol and improving its ability to remove harmful cholesterol from the body.1
Research shows that both HDL and LDL cholesterol have several different types. In general, smaller, denser LDL particles are more harmful than the large ones. And though all HDL particles are helpful, the larger, more mature HDL is seen as most protective.
In this randomized control study, 48 middle-aged women and men, normal and overweight, with elevated LDL cholesterol and normal HDL cholesterol levels at baseline, were assigned a diet that either included almonds (43 g/d) or a calorie-matched muffin as snacks. Researchers assessed each snack option on HDL cholesterol particle type, distribution, and transport of cholesterol to the liver for elimination.
Compared with the muffin snack group, normal weight participants in the almond snack group experienced an increase in alpha-1 HDL (larger, more mature HDL - generally a marker of heart health protection) as well as several measures related to cholesterol efflux. Cholesterol efflux is an important step in the reverse cholesterol transport pathway, which is thought to be a key mechanism by which HDL removes cholesterol from peripheral tissues to protect against heart disease. These effects were not seen among overweight individuals.