RESEARCH UPDATE: Time and Intervention Effects of Daily Almond Intake
A study2 by Korean researchers looked at the time and intervention effects of daily almond consumption on measures of body composition, blood lipid profiles and oxidative and inflammation indicators.
This study is an extension of a previously published 16-week randomized, controlled trial3 among 169 healthy, young adults (ages 20-39). The original study had three serial measurements (0, 8 and 16 weeks of intervention). This study added 4 additional weeks for a total of 20 weeks of intervention and included 85 out of the 169 participants.
Participants in the almond group (n = 57) consumed about 2 ounces (56 g) of almonds per day and participants in the control group (n = 28) were provided with high-carbohydrate control food items that had a similar number of calories as the 56 g of almonds. Participants were instructed to maintain their habitual dietary intake and usual level of physical activity and avoid consuming any additional nuts or nut products throughout the study. Participants ate almonds either as a snack or just before meals.
Compared to the high carb control food, participants in the almond group showed favorable changes on blood lipid profiles, including levels of triglycerides (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C). Participants in almond group also consumed significantly greater amount of vegetable protein, fiber, vitamin E, riboflavin, phosphorus, magnesium, monounsaturated fats and polyunsaturated fats compared with baseline after 20 weeks of consuming almonds. There were no significant differences between groups in energy intake.
Time, intervention, and interaction effects throughout the trial were analyzed using the mixed model. The almond group showed a significant time effects for changes in diastolic blood pressure and waist circumference, several bioimpedance measurements, including total body protein, fat-free mass, soft lean mass, skeletal muscle mass, and basal metabolic rate, and all of lipid profile parameters.
Like all studies, this one had some limitations:
- The isocaloric control food contained higher percentages of carbohydrates compared with almonds, which means it does not match the macronutrient composition of almonds. Further studies providing a control food item with matched macronutrient and fatty acid composition are needed.
- Almond and control food items provided were not able to be blinded, since participants consumed whole almonds or cookies.
- In addition, since the subjects were dropped out at the point of their compliances being under 80%, it was not possible to conduct intent-to-treat analysis.
- The current study has a sufficient duration to discern the effects of almonds on blood profiles but a longer-term study, over a year, with a parallel, randomized, controlled trial applying time-series measurements would provide additional valuable information about daily almond consumption.
In conclusion, the effects of almond appeared differently when using times repeated measures and the changes of lipid profiles achieved at different time points. Continuous consumption of almond for 20 weeks may improve serum lipid profiles and body composition in healthy young adults.